Laurelia novae-zelandiae "Pukatea"

[Mr. Lahey]

Anyone have any info? I UTFSE and came up with squat.

From Wikipedia:

"Pukateine is an alkaloid found in the bark of the New Zealand tree Laurelia novae-zelandiae ("Pukatea"). An extract from pukatea is used in traditional Māori herbal medicine as an analgesic,[1][2] and it is thought pukateine is the active component,[3] as it is similar in both structure and activity to alkaloids such as glaucine and tetrahydropalmatine which are found in Chinese medicinal herbs used as analgesics. Pukateine has multiple mechanisms of action, with the most prominent effects being as an agonist at the D2 dopamine receptor and antagonist at the α1 adrenergic receptor.[4][5]"













"Māori used the bark of the tall pukatea (Laurelia novae-zelandiae tree as a painkiller, boiling the inner layer to make a decoction. Pulped inner bark was also held in the mouth to ease toothache. Pukatea bark contains pukateine, which has a chemical structure similar to morphine. It was first isolated in 1910 by Bernard Aston, the first chemist at the Department of Agriculture"

[JackARoe]

Thanks M Lahey. I'm doing some digging too. Sounds interesting.